What a biotech team actually asks of trial intelligence
Ask the people who will use the platform for their last five questions. They usually fall into four groups.
- Competitive landscape. Which programs target the same mechanism or indication, in which phase, run by which sponsors.
- Design benchmarking. Which endpoints, comparators, durations and eligibility criteria did similar trials register before you lock your protocol.
- Timing. When did a competitor start, how fast is it enrolling, and has the completion date moved.
- Evidence for investors and partners. A landscape slide where each line traces to a record someone can open.
All four start with registry records. Investigator performance, site enrollment history and curated sponsor pipelines are a second layer that matters when you pick sites and negotiate with CROs, which is usually later than the first financing round.
The main options compared
Facts come from vendor pages and announcements, checked in October 2026. Where a price is not published, the table says so.
ClinicalEvidence
- Best for
- Cited competing-trial answers, trial tables and alerts for a small team
- Data
- ClinicalTrials.gov, EU Clinical Trials Register, WHO ICTRP and PubMed, refreshed daily
- Pricing
- Clinician 49 USD monthly or 24 USD per month billed yearly; Research Team 199 USD monthly or 99 USD per month billed yearly with 3 seats; Organization 499 USD monthly or 249 USD per month billed yearly with 10 seats
Citeline Trialtrove (Norstella)
- Best for
- Curated trial, sponsor and investigator intelligence; Trialtrove+ added an AI assistant called Ella in February 2025
- Data
- Curated vendor database
- Pricing
- Not public, enterprise contract
Cortellis Clinical Trials Intelligence (Clarivate)
- Best for
- Broad pipeline and trial intelligence inside a larger Clarivate suite
- Data
- Curated vendor database
- Pricing
- Not public, enterprise contract
ClinicalTrials.gov directly
- Best for
- Looking up a known study or running a structured filter
- Data
- One registry
- Pricing
- Free
Elicit
- Best for
- Structured extraction from papers; Clinical Trials feature reads ClinicalTrials.gov only
- Data
- Papers plus about 545,000 registry trials
- Pricing
- Pro 49 USD per user per month billed annually; Scale 169 USD; Enterprise custom
Each of these has a place. Trialtrove and Cortellis win on curation and on investigator and site detail. ClinicalTrials.gov wins on price. Elicit wins when the work is extraction from papers. ClinicalEvidence wins when the question is about registered trials across three registries and every statement has to cite its source.
Five criteria that decide the purchase
Coverage beyond one registry
A competitor may register a program in the EU or in the WHO network before it appears in the US registry. A single-registry tool shows an incomplete landscape. See how the WHO ICTRP and the EU Clinical Trials Register differ from ClinicalTrials.gov.
Citations you can open
Every claim in a landscape slide should point to an NCT number or a PMID. General chatbots can invent both, which we explain in why AI invents citations. Test any tool by opening ten citations.
Alerts
A landscape is a snapshot unless something tells you when it changes. Look for alerts on new trials and status changes tied to a saved question. The alerts feature shows how ClinicalEvidence handles it.
Seats and limits
Biotech teams are small and share work across clinical, regulatory and business development. Pooled answers across seats fit that better than per-user credits.
Export
The output ends up in a deck or a spreadsheet. Check that the trial table exports with identifiers intact, as in the export options.
When to start with a registry tool and when to buy an enterprise database
Start with a registry tool when you are pre-IND or in early clinical development, when the questions are about competing programs and designs, and when the budget cannot carry a five figure annual contract. A trial landscape built before protocol design often changes the endpoint or the comparator, which is worth more than any extra data field.
Add an enterprise database when you start selecting sites and investigators across many countries, when a partner or investor expects its sources, or when several programs need historical enrollment benchmarks. Many teams then keep the registry tool for fast questions and monitoring, because it costs little and answers in minutes.
Neither replaces a formal systematic review. Verification shows a reference exists and supports the sentence, and your team still appraises quality and relevance. For screening requirements, read about systematic review software.
A practical setup for a team of five
Put the indication and mechanism into a saved question in ClinicalEvidence and read the first cited answer. Open the trial table, filter to phase 2 and 3, and export it. Set an alert so the clinical lead hears about new entrants. When business development needs to follow what competitors publish on their own websites, such as pipeline pages and press releases, a tool that can monitor competitor websites for changes complements the registry view. Treat both as leads and verify them against the record before they reach a board deck.
Questions biotech teams ask
What is a clinical trial intelligence platform?
A clinical trial intelligence platform collects and organizes data on trials, sponsors, sites and investigators so teams can analyze competitors, design studies and plan operations. Some platforms curate their own database, others read public registries and add search, alerts and analysis on top.
How much does a clinical trial intelligence platform cost?
Enterprise platforms such as Trialtrove and Cortellis do not publish prices and sell by contract. ClinicalEvidence lists plans from 49 USD monthly or 24 USD per month billed yearly for one person, and 199 USD monthly or 99 USD per month billed yearly for a team of three.
Is ClinicalTrials.gov enough for competitive intelligence?
It is enough for known studies, but it covers one registry and has no cited summary or change alerts. Competitors also register in the EU Clinical Trials Register and WHO ICTRP, so a complete landscape needs all three.
Can AI replace Trialtrove?
Not fully. AI over public registries covers competing trials, status and designs. Curated platforms add investigator and site intelligence that registries do not hold. Many small teams start with the former and add the latter when site selection begins.
How often should a competitive trial landscape be updated?
Review it at every protocol decision and set alerts so changes arrive between reviews. Status changes, new entrants and moved completion dates can alter a comparator choice or a timeline within weeks.