Clinical feasibility and trial landscape before protocol design
See what similar trials chose for endpoints and comparators, how many patients they enrolled and where they ran, before your protocol is written, with every statement cited to its registry record.
Feasibility work at CROs and sponsors
Feasibility and clinical operations teams are asked to answer a sponsor's questions fast and well. How many active trials compete for the same patients, which comparator is standard in recent phase 3 studies, what primary endpoint regulators have seen before, and which countries have recruited for this indication. A proposal or a protocol synopsis often depends on the answer.
The raw material is public, but scattered. ClinicalTrials.gov, the EU Clinical Trials Register and CTIS and WHO ICTRP each hold part of the picture, and published results sit in PubMed. Building a landscape table by hand means hours of exporting, deduplicating and reading, and the result is hard to update when the sponsor changes the population.
- Competing trials in the same indication affect recruitment
- Endpoint and comparator choices of similar trials inform protocol design
- Target enrolment and site countries hint at realistic recruitment
- Every figure in a feasibility report has to trace back to a record
A typical feasibility workflow in ClinicalEvidence
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1. Ask the landscape question, for example which phase 2 and phase 3 trials in moderate to severe ulcerative colitis are recruiting or recently completed, and what they use as primary endpoint.
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2. Read the cited answer, with NCT numbers or PMIDs on every sentence and each citation checked before the answer is shown.
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3. Open the trial table. Filter by phase, status, sponsor type, country and date range, then sort by enrolment or start date.
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4. Review interventions, comparators and primary and secondary endpoints column by column to see what similar trials chose.
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5. Check locations to see enrolment and sites by country across the competing studies.
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6. Export the table to XLSX or bulk CSV for the feasibility report, and set an alert on the question for changes during study start-up.
Features that matter for feasibility teams
- A clinical trial table with phase, population, interventions, endpoints, sponsor, status, enrolment, dates and locations
- Filters for condition, intervention, phase, status, study type, date range, sponsor type, country and results available
- Comparisons of two to four interventions to see comparators and outcomes side by side
- Export of trial data to CSV, XLSX and bulk CSV
- Shared workspaces so the whole proposal team works from the same evidence
Read more about trial landscape analysis before protocol design and about clinical trial search across registries.
Recommended plan for CRO feasibility teams
Organization costs 499 USD per month, or 249 USD per month billed yearly (2 988 USD). It includes 2 000 cited answers per month pooled across 10 seats, up to 250 per day, trial tables of up to 500 studies per answer, 100 alerts, bulk CSV export, an audit log and invoicing.
A smaller feasibility group can start with Research Team at 199 USD per month, or 99 USD per month billed yearly (1 188 USD), with 800 cited answers pooled, 3 seats and trial tables of up to 200 studies. All limits are on the pricing page.
Questions from feasibility teams
Does ClinicalEvidence show sites and countries for competing trials?
Yes. The trial table lists locations from the registry records, so you can filter by country and see where similar trials recruit.
Can it estimate recruitment rates for my trial?
No. It shows target and actual enrolment, dates and locations as registered. Your team uses those facts in its own feasibility assessment.
How large can a landscape table be?
It depends on the plan: up to 50 studies per answer on Clinician, 200 on Research Team, 500 on Organization and 1 000 on Enterprise.
Start your next feasibility assessment with cited trial data
Create your account and build a landscape table for your indication today.