A cited answer
Every sentence carries the EudraCT numbers, NCT numbers or PMIDs behind it.
EU Clinical Trial Register evidence in cited answers
European trials matter for every global evidence question, yet they are easy to miss when you only search US records. ClinicalEvidence includes EU Clinical Trials Register records where licences allow, cites them by EudraCT number and places them in the same trial table as ClinicalTrials.gov studies and published papers.
Why European trial records are hard to search by hand
The European picture changed with the Clinical Trials Regulation, and trial information now sits in two systems with different identifiers, formats and search screens. Matching a European record to its US registration or its journal article usually means searching each source separately and comparing titles, sponsors and dates.
- Older trials and newer trials live in different European systems
- The same trial may carry a EudraCT number, an EU CT number and an NCT number
- Summary results are posted for some trials and published only in journals for others
- Exports need cleaning before European and US records can sit side by side
What the EU Clinical Trials Register (EU CTR) holds
The EU Clinical Trials Register is the public register run by the European Medicines Agency for trials authorised under the former Clinical Trials Directive 2001/20/EC. Its records come from the EudraCT database.
- Interventional clinical trials on medicinal products in the European Union and the European Economic Area authorised under the Directive
- Trials conducted outside the EU when they are part of an agreed paediatric investigation plan
- Summary results for many trials, posted by the sponsor
- Phase 1 trials in adults are not shown publicly, while paediatric trials are
Each trial is identified by a EudraCT number, written as the year followed by six digits and two check digits. A trial run in several member states has one EudraCT number and a protocol record for each country.
The transition to CTIS under Regulation (EU) No 536/2014
The Clinical Trials Regulation (EU) No 536/2014 has applied since 31 January 2022. It introduced the Clinical Trials Information System (CTIS) as the single entry point for submitting and publishing trial information in the EU and EEA. New trial applications have had to go through CTIS since 31 January 2023, and trials still running under the Directive had to move to the Regulation by the end of the three year transition in January 2025.
- Trials submitted through CTIS carry an EU CT number instead of a EudraCT number
- The EU Clinical Trials Register remains the public record of trials authorised under the Directive, including their posted results
- A complete European view needs both the older register and the newer system in mind
When you search with ClinicalEvidence, the "Sources searched" panel shows exactly which sources contributed to each answer, so you always know whether European records were part of it.
How ClinicalEvidence includes EU records
Our index includes EU Clinical Trials Register records where licences allow, alongside ClinicalTrials.gov, the WHO ICTRP, PubMed and the open access subset of PubMed Central. It is refreshed every day.
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Answers cite European trials by their EudraCT number and link to the source record
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Where a trial is also registered on ClinicalTrials.gov, both identifiers can appear in the trial table
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Filter by country to focus on trials with sites in specific member states
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Automatic citation verification checks each ID exists in the index and that the cited passage supports the sentence
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When the index holds no evidence, you are told so plainly, never answered from model memory
The WHO ICTRP adds records from other national and regional registries, which helps catch trials registered outside both systems. Read how to search the WHO ICTRP for the details.
What you see for a European evidence question
A trial table across regions
European and US trials in one clinical trial table with phase, population, interventions, endpoints, results posted, sponsor, status, enrolment, dates and locations.
Comparison and alerts
Compare interventions across European and US trials, and save the question to get an email when new matching records appear.
An independent tool, not affiliated with the EMA
ClinicalEvidence is not affiliated with, endorsed by or operated by the European Medicines Agency, the EU Clinical Trials Register or CTIS. We index public records where licences allow and link every claim back to its source.
Who needs EU Clinical Trial Register evidence
- Clinical development teams planning trials with European sites
- CRO feasibility leads checking competing European recruitment
- Medical affairs teams answering questions for European markets
- HEOR and regulatory consultants preparing evidence for European submissions
ClinicalEvidence is a professional research tool and does not give medical advice.
Plans for European trial evidence
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- Enterprise, 1 490 USD per month or 745 USD per month billed yearly (8 940 USD)
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EU Clinical Trial Register questions
Does ClinicalEvidence search the EU Clinical Trials Register?
Yes. EU Clinical Trials Register records are part of our index where licences allow, and each answer lists the sources actually searched for that question.
What is a EudraCT number?
It is the identifier of a trial in the EudraCT database used under the former Clinical Trials Directive, written as the year followed by six digits and two check digits. Trials submitted through CTIS carry an EU CT number instead.
Why are some European phase 1 trials missing?
The EU Clinical Trials Register does not publicly show phase 1 trials in adults. Paediatric trials, including phase 1, are shown.
Is ClinicalEvidence affiliated with the EMA?
No. ClinicalEvidence is an independent tool and is not affiliated with or endorsed by the European Medicines Agency.
Can I see European and US trials together?
Yes. The trial table puts studies from every searched source in one place, and you can filter by country, phase, status and results available.
Bring European trials into your next answer
Ask a question in the one-time demo and see which records it cites.